Trial intelligence / Profile preview

Safety and Efficacy of AMG 397 in Relapsed/Refractory Hematological Malignancies

NCT03465540Phase 1Terminated

Sponsor
Amgen
Start
Aug 2018
Primary completion
Jul 2019
Modality
Small Molecules
Countries
6
01

Overview

Phase 1, open-label trial of murizatoclax in multiple myeloma (MM), acute myeloid leukemia (AML), non-Hodgkin lymphoma (NHL) and 1 more (8 arms), sponsored by Amgen. Primary endpoints: Number of Participants Who Experienced a Dose-limiting Toxicity at 28 days and Number of Participants Who Experienced a Treatment-emergent Adverse Event. Started Aug 2018; status: terminated.

02

Drugs

murizatoclax
03

Conditions

multiple myeloma (MM)acute myeloid leukemia (AML)non-Hodgkin lymphoma (NHL)myelodysplastic syndrome (MDS)

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