Trial intelligence / Profile preview

Ad5 PSA/MUC1/Brachyury Vaccine in mCRPC

NCT03481816Phase 1Completed

Sponsor
National Cancer Institute
Start
Jul 2018
Primary completion
Jan 2020
Modality
Gene Editing, Viral Vector Vaccines, Gene Silencing
Countries
1
01

Overview

Phase 1, open-label trial of adenovirus PSA vaccine, ETBX-061 and ETBX-051 in metastatic castration-resistant prostate cancer (mCRPC), sponsored by National Cancer Institute. Primary endpoints: Dose-Limiting Toxicities at 4 weeks and Recommended Phase 2 Dose at 4 weeks. Started Jul 2018; status: completed.

02

Drugs

adenovirus PSA vaccineETBX-061ETBX-051
03

Conditions

metastatic castration-resistant prostate cancer (mCRPC)

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