Trial intelligence / Profile preview

Non-TBI Conditioning for NGS-MRD Negative B-ALL

NCT03509961Phase 2Recruiting

Sponsor
Pediatric Transplant and Cellular Therapy Consortium
Start
Aug 2018
Primary completion
Jul 2025
Modality
Orthosteric Ligands, Metabolically Activated Prodrugs
Countries
1
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Overview

Phase 2, open-label trial of busulfan, fludarabine and thiotepa in B cell acute lymphoblastic leukemia (B-ALL) (2 arms), sponsored by Pediatric Transplant and Cellular Therapy Consortium. Primary endpoint: Event-free Survival at 2 years. Started Aug 2018; status: recruiting.

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Drugs

busulfanfludarabinethiotepa
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Conditions

B cell acute lymphoblastic leukemia (B-ALL)

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