Trial intelligence / Profile preview

PRISM: Targeted Agents + Acalabrutinib in R/R Aggressive NHL

NCT03527147Phase 1Completed

Sponsor
Acerta Pharma
Start
Jun 2018
Primary completion
Mar 2021
Modality
Prophylactic Vaccines, Monoclonal Antibodies, Modified DNA Oligonucleotides
Countries
2
01

Overview

Phase 1, open-label trial of danvatirsen, ceralasertib, magrolimab, AZD5153 and acalabrutinib tablet (Variant 1) in non-Hodgkin lymphoma (NHL) (4 arms), sponsored by Acerta Pharma. Primary endpoint: Incidence of adverse events at 1 year. Started Jun 2018; status: completed.

02

Drugs

danvatirsenceralasertibmagrolimabAZD5153acalabrutinib tablet (Variant 1)
03

Conditions

non-Hodgkin lymphoma (NHL)

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