Trial intelligence / Profile preview

DDI Study of Belumosudil with Itraconazole, Rifampicin, Rabeprazole, and Omeprazole

NCT03530995Phase 1Completed

Sponsor
Kadmon
Start
Apr 2018
Primary completion
Feb 2019
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, open-label trial of belumosudil in chronic graft-versus-host disease (cGVHD) (2 cohorts), sponsored by Kadmon. Primary endpoints: Maximum Plasma Concentration (Cmax) of KD025 and Metabolites and Area Under the Curve (AUC) of KD025 and Metabolites. Started Apr 2018; status: completed.

02

Drugs

belumosudil
03

Conditions

chronic graft-versus-host disease (cGVHD)

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