Trial intelligence / Profile preview

Allo-HSCT with α/β T-cell Depletion and Reduced Intensity Conditioning for Hematologic Malignancies and Aplastic Anemia

NCT03531736Phase 1Active, not recruiting

Sponsor
Memorial Sloan Kettering Cancer Center
Start
May 2018
Primary completion
May 2027
Modality
Stem Cell Therapies
Countries
1
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Overview

Phase 1, open-label, single-arm trial of antithymocyte globulin, fludarabine, cyclophosphamide and rituximab in hematologic malignancy and aplastic anemia, sponsored by Memorial Sloan Kettering Cancer Center. Primary endpoint: Rate of donor Neutrophil Engraftment at 30 days. Started May 2018; status: active, not recruiting.

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Drugs

antithymocyte globulinfludarabinecyclophosphamiderituximab
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Conditions

hematologic malignancyaplastic anemia

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