Trial intelligence / Profile preview

CAMILLA: Cabozantinib + Durvalumab +/- Tremelimumab in Advanced GI Malignancies

NCT03539822Phase 2Recruiting

Start
Oct 2018
Primary completion
Jun 2028
Modality
Antibody Conjugates, Engineered Antibody Formats, PD-1/PD-L1 Inhibitors
Countries
1
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Overview

Phase 2, open-label trial of cabozantinib and durvalumab in gastric cancer (GC), esophageal adenocarcinoma (EAC), hepatocellular carcinoma (HCC) and 1 more (4 cohorts). Primary endpoints: Maximum Tolerated Dose at 9 months and Overall Response Rate. Started Oct 2018; status: recruiting.

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Drugs

cabozantinibdurvalumab
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Conditions

gastric cancer (GC)esophageal adenocarcinoma (EAC)hepatocellular carcinoma (HCC)colorectal cancer (CRC)

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