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CRISPR-Cas9 PD-1/TCR KO anti-mesothelin CAR-T in Solid Tumors

NCT03545815Phase 1Unknown

Sponsor
Chinese PLA General Hospital
Start
Mar 2018
Primary completion
Oct 2020
Modality
CAR-T Cells
Countries
1
01

Overview

Phase 1, open-label trial of anti-mesothelin CAR vector-transduced autologous T lymphocytes in solid tumor, sponsored by Chinese PLA General Hospital. Primary endpoint: Study of related adverse events at 24 weeks. Status: unknown.

02

Drugs

anti-mesothelin CAR vector-transduced autologous T lymphocytes
03

Conditions

solid tumor

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