Trial intelligence / Profile preview

FLT PET/MR to Predict Graft Failure and GVHD in BMT

NCT03546556Phase 1Terminated

Sponsor
UNC Lineberger Comprehensive Cancer Center
Start
Jan 2017
Primary completion
Mar 2020
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, open-label trial of fluorothymidine F-18 in graft-versus-host disease (GVHD) and Graft failure (2 arms), sponsored by UNC Lineberger Comprehensive Cancer Center. Primary endpoints: Overall FLT-PET Bone Marrow Signal at 35 days and Overall FLT-PET Signal Intensity within Host Secondary Lymphoid Sites at 100 days. Started Jan 2017; status: terminated.

02

Drugs

fluorothymidine F-18
03

Conditions

graft-versus-host disease (GVHD)Graft failure

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