Trial intelligence / Profile preview

MK-4830 with pembrolizumab in advanced solid tumors

NCT03564691Phase 1Completed

Sponsor
Merck & Co.
Start
Jul 2018
Primary completion
Sep 2025
Modality
Immune Checkpoint Inhibitors
Countries
12
01

Overview

Phase 1, open-label trial of mk-4830 in pancreatic adenocarcinoma (PDAC), mesothelioma, glioblastoma (GBM) and 7 more (17 arms), sponsored by Merck & Co. Primary endpoints: Dose-Limiting Toxicities at 21 days, Adverse Events at 27 months and 3 more. Started Jul 2018; status: completed.

02

Drugs

mk-4830
03

Conditions

pancreatic adenocarcinoma (PDAC)mesotheliomaglioblastoma (GBM)head and neck squamous cell carcinoma (HNSCC)non-small cell lung cancer (NSCLC)

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