Trial intelligence / Profile preview

iExosomes in Metastatic Pancreatic Cancer with KrasG12D Mutation

NCT03608631Phase 2Recruiting

Sponsor
University of Texas MD Anderson Cancer Center
Start
Jan 2021
Primary completion
Apr 2027
Countries
1
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Overview

Phase 2, open-label, single-arm trial of mesenchymal stromal cells-derived exosomes with kras g12d sirna in pancreatic ductal adenocarcinoma (PDAC), sponsored by University of Texas MD Anderson Cancer Center. Primary endpoints: Maximum Tolerated Dose at 4 weeks, Dose-Limiting Toxicities at 4 weeks and 3 more. Started Jan 2021; status: recruiting.

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Drugs

mesenchymal stromal cells-derived exosomes with kras g12d sirna
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Conditions

pancreatic ductal adenocarcinoma (PDAC)

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