Trial intelligence / Profile preview

Diesel Exhaust and Glucocorticoid Resistance in Asthma

NCT03615742Phase 4Recruiting

Sponsor
University of British Columbia
Start
Dec 2018
Primary completion
Dec 2025
Modality
Orthosteric Ligands
Countries
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Overview

Phase 4, randomised, double-blind trial of budesonide in asthma (4 arms), sponsored by University of British Columbia. Primary endpoint: Change in DNA methylation, mRNA and protein expression attributable to diesel exhaust and inhaled corticosteroid at 6 hours. Started Dec 2018; status: recruiting.

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Drugs

budesonide
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Conditions

asthma

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