Trial intelligence / Profile preview

CD4 CAR+CCR5 ZFN T-cells in HIV-infected Subjects

NCT03617198Phase 1Active, not recruiting

Sponsor
University of Pennsylvania
Start
Jul 2019
Primary completion
Dec 2026
Modality
Gene Editing, Gene Silencing, CAR-T Cells
Countries
1
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Overview

Phase 1, randomised, open-label trial of CD4 CAR+CCR5 ZFN T-cells in human immunodeficiency virus infection (HIV) (2 cohorts), sponsored by University of Pennsylvania. Primary endpoint: Number of subjects with treatment related adverse events up to 5 years. Started Jul 2019; status: active, not recruiting.

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Drugs

CD4 CAR+CCR5 ZFN T-cells
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Conditions

human immunodeficiency virus infection (HIV)

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