Trial intelligence / Profile preview

DURTRE-RAD: Durvalumab +/- Tremelimumab with Radiotherapy in HNSCC

NCT03624231Phase 2Completed

Start
Aug 2018
Primary completion
Aug 2023
Modality
Antibody Conjugates, Engineered Antibody Formats, PD-1/PD-L1 Inhibitors
Countries
1
01

Overview

Phase 2, randomised, open-label trial in squamous cell carcinoma of the head and neck (HNSCC) comparing Durvalumab + Tremelimumab + RT with Durvalumab + RT (2 arms). Primary endpoints: Progression-Free Survival at 1 year and Treatment Discontinuation due to Toxicity. Started Aug 2018; status: completed.

02

Drugs

durvalumabtremelimumab
03

Conditions

squamous cell carcinoma of the head and neck (HNSCC)

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