Trial intelligence / Profile preview

Navtemadlin (KRT-232) in Relapsed/Refractory Myelofibrosis

NCT03662126Phase 3Recruiting

Sponsor
Kartos Therapeutics
Start
Jan 2019
Primary completion
Dec 2023
Modality
Small Molecules
Countries
28
01

Overview

Phase 3, randomised, open-label trial of navtemadlin in primary myelofibrosis (PMF), post-polycythemia vera myelofibrosis (PPV-MF) and post-essential thrombocythemia myelofibrosis (PET-MF) (6 arms), sponsored by Kartos Therapeutics. Primary endpoint: Spleen Volume Reduction at 24 weeks. Started Jan 2019; status: recruiting.

02

Drugs

navtemadlin
03

Conditions

primary myelofibrosis (PMF)post-polycythemia vera myelofibrosis (PPV-MF)post-essential thrombocythemia myelofibrosis (PET-MF)

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