Trial intelligence / Profile preview

ACTH Effect on VEGF in Healthy Children

NCT03709381Phase 1Completed

Sponsor
Nationwide Children's Hospital
Start
Oct 2017
Primary completion
Oct 2018
Modality
Peptides, Small Molecules
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of tetracosactide hexaacetate in adrenal insufficiency (AI), osteopenia, osteoporosis and 2 more, sponsored by Nationwide Children's Hospital. Primary endpoint: Difference between VEGF levels at baseline and the peak VEGF level after low dose cosyntropin administration at 60 minutes. Started Oct 2017; status: completed.

02

Drugs

tetracosactide hexaacetate
03

Conditions

adrenal insufficiency (AI)osteopeniaosteoporosisosteonecrosisSecondary adrenal insufficiency (SAI)

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