Trial intelligence / Profile preview

Triple bNAb Combination (PGT121, VRC07-523LS, PGDM1400) in HIV

NCT03721510Phase 2Completed

Sponsor
International AIDS Vaccine Initiative
Start
Dec 2018
Primary completion
Oct 2021
Modality
Engineered Antibody Formats, Antibody Conjugates, Monoclonal Antibodies
Countries
1
01

Overview

Phase 2, open-label trial of PGT121, VRC07-523LS and PGDM1400LS in human immunodeficiency virus infection (HIV) (3 arms), sponsored by International AIDS Vaccine Initiative. Primary endpoints: Proportion of volunteers with moderate or greater reactogenicity, Proportion of volunteers with adverse events (AEs) at 56 days and 5 more. Started Dec 2018; status: completed.

02

Drugs

PGT121VRC07-523LSPGDM1400LS
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Conditions

human immunodeficiency virus infection (HIV)

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