Trial intelligence / Profile preview

Pharmacokinetics of [14C]-Evobrutinib in Healthy Participants

NCT03725072Phase 1Completed

Sponsor
Merck KGaA
Start
Oct 2018
Primary completion
Dec 2018
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of evobrutinib in multiple sclerosis (MS), rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE), sponsored by Merck KGaA. Primary endpoints: Total Radioactivity Recovery Rate of Evobrutinib, Total Radioactivity and its Metabolites, Percentage Excretion of Evobrutinib, Total Radioactivity and its Metabolites in Urine and Feces and 11 more. Started Oct 2018; status: completed.

02

Drugs

evobrutinib
03

Conditions

multiple sclerosis (MS)rheumatoid arthritis (RA)systemic lupus erythematosus (SLE)

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