Trial intelligence / Profile preview

mDC3 Vaccine for Resected Hypermutated Colorectal Cancer

NCT03730948Phase 1Terminated

Sponsor
University of Pennsylvania
Start
Mar 2019
Primary completion
Feb 2022
Modality
Whole Cell Cancer Vaccines, Dendritic Cell Vaccines
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of mDC3 vaccine in colorectal cancer (CRC), sponsored by University of Pennsylvania. Primary endpoints: Changes in Numbers of Peptide-specific CD8+ T Cells (Post-vaccine Immune Response) and Adverse Events Experienced by Subjects at 12 months. Started Mar 2019; status: terminated.

02

Drugs

mDC3 vaccine
03

Conditions

colorectal cancer (CRC)

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