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Nitrous Oxide for Acute Suicidal Ideation in Unipolar Depression
NCT03736538Phase 1Enrolling by invitation
- Sponsor
- Washington University School of Medicine
- Start
- Oct 2018
- Primary completion
- Sep 2026
- Modality
- Small Molecules
- Countries
- 1
01
Overview
Phase 1, randomised, double-blind trial in major depressive disorder (MDD) and suicidal ideation comparing Nitrous Oxide + TAU with Placebo Gas + TAU (2 arms). Primary endpoints: Severity and number of adverse events at 60 days, Differential change in suicidal ideation at 7 days and 1 more. Started Oct 2018; status: enrolling by invitation.
02
Drugs
nitrous oxide
03
Conditions
major depressive disorder (MDD)suicidal ideation
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