Trial intelligence / Profile preview

Durvalumab With or Without Tremelimumab as Neoadjuvant Therapy in Resectable Head and Neck Cancer

NCT03737968Phase 2Unknown

Sponsor
Yonsei University
Start
Jan 2019
Primary completion
Oct 2023
Modality
Antibody Conjugates, Engineered Antibody Formats, PD-1/PD-L1 Inhibitors
Countries
1
01

Overview

Phase 2, randomised, open-label trial in head and neck squamous cell carcinoma (HNSCC) comparing Durvalumab monotherapy Arm with Durvalumab + tremelimumab combination therapy Arm (2 arms). Primary endpoints: Locoregional Relapse Rate up to 2 years and Distant Metastatic Rate up to 2 years. Status: unknown.

02

Drugs

durvalumabtremelimumab
03

Conditions

head and neck squamous cell carcinoma (HNSCC)

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