Trial intelligence / Profile preview

Safety and PK of MK-4334 in Alzheimer's Clinical Syndrome

NCT03740178Phase 1Withdrawn

Sponsor
Merck & Co.
Start
Sep 2019
Primary completion
Feb 2020
Modality
Small Molecules
01

Overview

Phase 1, randomised, double-blind trial in Alzheimer's disease (AD) and Mild Cognitive Impairment (MCI) comparing Donepezil + MK-4334 with Donepezil + Placebo (2 arms). Primary endpoints: Number of Participants Experiencing an Adverse Event up to 42 days and Number of Participants Discontinuing Study Treatment due to an Adverse Event up to 14 days. Planned start Sep 2019; status: withdrawn.

02

Drugs

BNC375
03

Conditions

Alzheimer's disease (AD)Mild Cognitive Impairment (MCI)

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