Trial intelligence / Profile preview

Pirtobrutinib in previously treated CLL/SLL and NHL

NCT03740529Phase 2Completed

Sponsor
Loxo Oncology
Start
Mar 2019
Primary completion
Jan 2025
Modality
Small Molecules
Countries
10
01

Overview

Phase 2, open-label trial of pirtobrutinib in chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), non-Hodgkin lymphoma (NHL) and 3 more (11 arms), sponsored by Loxo Oncology. Primary endpoints: Maximum Tolerated Dose at 24 months, Recommended Phase 2 Dose at 24 months and 2 more. Started Mar 2019; status: completed.

02

Drugs

pirtobrutinib
03

Conditions

chronic lymphocytic leukemia (CLL)small lymphocytic lymphoma (SLL)non-Hodgkin lymphoma (NHL)Waldenstrom macroglobulinemia (WM)mantle cell lymphoma (MCL)

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