Trial intelligence / Profile preview

WIRE: Window of Opportunity Trial in Renal Cell Cancer

NCT03741426Phase 2Recruiting

Sponsor
Cambridge Clinical Trials Unit
Start
Jul 2020
Primary completion
Dec 2027
Modality
Antibody Conjugates, Engineered Antibody Formats, PD-1/PD-L1 Inhibitors
Countries
1
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Overview

Phase 2, open-label trial of olaparib, cediranib, volrustomig and rilvegostomig in renal cell carcinoma (RCC) (5 arms), sponsored by Cambridge Clinical Trials Unit. Primary endpoints: Proof-of-Mechanism (ktrans) and Proof-of-Mechanism (CD8). Started Jul 2020; status: recruiting.

02

Drugs

olaparibcediranibvolrustomigrilvegostomig
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Conditions

renal cell carcinoma (RCC)

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