Trial intelligence / Profile preview

Pelican: Ad/MG1-MAGEA3 + Pembrolizumab in Advanced Skin Cancers

NCT03773744Phase 1Withdrawn

Sponsor
Turnstone Biologics
Start
Feb 2020
Primary completion
Oct 2020
Modality
Prophylactic Vaccines, Viral Vectors, Oncolytic Viruses
01

Overview

Phase 1, open-label trial of Ad-MAGEA3 and mg1-magea3 in melanoma and cutaneous squamous cell carcinoma (cSCC) (2 arms), sponsored by Turnstone Biologics. Primary endpoints: Safety of Ad/MG1-MAGEA3 administration at 6 months and Maximum Tolerated Dose / Maximum Feasible Dose at 5 weeks. Planned start Feb 2020; status: withdrawn.

02

Drugs

Ad-MAGEA3mg1-magea3
03

Conditions

melanomacutaneous squamous cell carcinoma (cSCC)

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