Trial intelligence / Profile preview

HIV-1 Env Model Immunogens Prime-Boost Study

NCT03816137Phase 1Completed

Sponsor
Imperial College London
Start
Mar 2019
Primary completion
Dec 2022
Modality
Nanoparticles, Recombinant Proteins and Enzymes, Therapeutic Vaccines
Countries
1
01

Overview

Phase 1, randomised trial of ConM SOSIP, ConS UFO, mosaic sosips, AMC011 SOSIP and 763 SOSIP in human immunodeficiency virus infection (HIV) (13 arms), sponsored by Imperial College London. Primary endpoints: Neutralising antibodies to virus expressing ConM and ConS envelopes at 6 months, Neutralising antibodies to virus expressing Mosaic envelopes at 12 months and 1 more. Started Mar 2019; status: completed.

02

Drugs

ConM SOSIPConS UFOmosaic sosipsAMC011 SOSIP763 SOSIP
03

Conditions

human immunodeficiency virus infection (HIV)

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