Trial intelligence / Profile preview

Immune Checkpoint Blockade for Kidney Transplant Recipients With Advanced Cancers

NCT03816332Phase 1Active, not recruiting

Sponsor
National Cancer Institute
Start
Nov 2019
Primary completion
Oct 2022
Modality
Monoclonal Antibodies
Countries
1
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Overview

Phase 1, open-label, single-arm trial of nivolumab and ipilimumab in melanoma, basal cell carcinoma (BCC), Merkel cell carcinoma (MCC) and 2 more, sponsored by National Cancer Institute. Primary endpoint: Number and Percentage of Outcome Responses (CR, PR, SD without allograft loss) at 16 weeks. Started Nov 2019; status: active, not recruiting.

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Drugs

nivolumabipilimumab
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Conditions

melanomabasal cell carcinoma (BCC)Merkel cell carcinoma (MCC)squamous cell carcinoma (SCC)microsatellite instability-high cancer

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Study design & results

Available in the Gosset platform where reported.

Competitive context

Available in the Gosset platform where reported.

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