Trial intelligence / Profile preview

ZW49 in HER2-expressing Cancers

NCT03821233Phase 1Completed

Sponsor
Zymeworks Inc.
Start
Apr 2019
Primary completion
Sep 2024
Modality
Bispecific Antibodies, Recombinant Proteins and Enzymes, Antibody-Drug Conjugates (ADCs)
Countries
4
01

Overview

Phase 1, open-label, single-arm trial of zanidatamab zovodotin in breast cancer, gastroesophageal adenocarcinoma and Solid tumors, sponsored by Zymeworks Inc. Primary endpoints: Incidence of Dose-Limiting Toxicities up to 4 weeks, Incidence of Adverse Events up to 7 months and 3 more. Started Apr 2019; status: completed.

02

Drugs

zanidatamab zovodotin
03

Conditions

breast cancergastroesophageal adenocarcinomaSolid tumors

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