Trial intelligence / Profile preview

Nitrous Oxide in OCD

NCT03826693Phase 2

Key facts

Status
Recruiting
Start
Apr 2021
Primary completion
Sep 2026
Countries
1
Sponsor
Stanford University
Modality
Small Molecules
Conditions
obsessive compulsive disorder (OCD)
01

Overview

Phase 2, randomised, triple-blind trial of nitrous oxide in obsessive compulsive disorder (OCD) (2 arms), sponsored by Stanford University. Primary endpoint: Yale-Brown Obsessive Compulsive Scale at 1 week. Started Apr 2021; status: recruiting.

02

Design

2 arms
Study design
RandomizedTriple-blind
  • Nitrous Oxide Arm

    Participants receive nitrous oxide in the first session and nitrogen in the second (or vice versa).

  • Nitrogen Arm

    Participants receive nitrogen in the first session and nitrous oxide in the second (or vice versa).

03

Who it enrols

Adults aged 18-65 with a primary diagnosis of OCD of sufficient severity who are able to tolerate a treatment-free period.

04

Endpoints

Primary

  • Yale-Brown Obsessive Compulsive Scale

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