Trial intelligence / Profile preview

Pembrolizumab plus Enzalutamide in mCRPC (KEYNOTE-641)

NCT03834493Phase 3Terminated

Sponsor
Merck & Co.
Start
Jul 2019
Primary completion
Dec 2022
Modality
Immune Checkpoint Inhibitors, Recombinant Proteins and Enzymes
Countries
28
01

Overview

Phase 3, randomised, double-blind trial in metastatic castration-resistant prostate cancer (mCRPC) comparing Pembrolizumab + Enzalutamide with Placebo + Enzalutamide (2 arms). Primary endpoints: Overall Survival up to 40 months and Radiographic Progression-free Survival up to 40 months. Started Jul 2019; status: terminated.

02

Drugs

03

Conditions

metastatic castration-resistant prostate cancer (mCRPC)

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