Trial intelligence / Profile preview

PHYOX2: Nedosiran in Primary Hyperoxaluria

NCT03847909Phase 2Completed

Sponsor
Novo Nordisk
Start
Oct 2019
Primary completion
Jun 2021
Modality
Conjugated siRNA, Chemically Modified siRNA
Countries
15
01

Overview

Phase 2, randomised, double-blind trial in Primary Hyperoxaluria Type 1 (PH1) and Primary Hyperoxaluria Type 2 (PH2) comparing Nedosiran with Placebo (2 arms). Primary endpoint: Area Under the Curve of Percent Change from Baseline in 24-Hour Urinary Oxalate. Started Oct 2019; status: completed.

02

Drugs

nedosiran
03

Conditions

Primary Hyperoxaluria Type 1 (PH1)Primary Hyperoxaluria Type 2 (PH2)

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