Trial intelligence / Profile preview

HOPE9: Presurgical 9-valent HPV Vaccination in Women Treated With LEEP

NCT03848039Phase 3Not yet recruiting

Start
Dec 2020
Primary completion
Dec 2022
Modality
Vaccines & Immunotherapeutics
01

Overview

Phase 3, randomised, double-blind trial in cervical intraepithelial neoplasia (CIN) and Cervical Cancer (CC) comparing Gardasil-9 with Placebo (2 arms). Primary endpoint: Cumulative recurrence of CIN2+ after conization at 5 years. Planned start Dec 2020; status: not yet recruiting.

02

Drugs

recombinant human papillomavirus 9-valent vaccine
03

Conditions

cervical intraepithelial neoplasia (CIN)Cervical Cancer (CC)

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