Trial intelligence / Profile preview

Pharmacokinetics of Intranasal Naltrexone and Naloxone

NCT03851731Phase 1Completed

Sponsor
National Institute on Drug Abuse
Start
Oct 2015
Primary completion
Nov 2015
Modality
Orthosteric Ligands
01

Overview

Phase 1, randomised, open-label trial of naltrexone transdermal patch and naloxone in opioid overdose (3 arms), sponsored by National Institute on Drug Abuse. Primary endpoints: Maximum Serum Concentration at 12 days, Area Under the Plasma Concentration Time Curve from Zero to Time t at 12 days and 1 more. Started Oct 2015; status: completed.

02

Drugs

naltrexone transdermal patchnaloxone
03

Conditions

opioid overdose

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