Trial intelligence / Profile preview

Sodium-Glucose CoTransporter 2 (sGLT2) Inhibitor and Endogenous Ketone Production

NCT03852901Phase 1Completed

Sponsor
National Institute on Aging
Start
Mar 2019
Primary completion
Nov 2020
Modality
Small Molecules
Countries
1
01

Overview

Phase 1, open-label, single-arm trial of empagliflozin in Alzheimer's disease (AD) and Mild Cognitive Impairment (MCI), sponsored by National Institute on Aging. Primary endpoint: Change in Serum β-hydroxybutyrate (BHB) at 14 days. Started Mar 2019; status: completed.

02

Drugs

empagliflozin
03

Conditions

Alzheimer's disease (AD)Mild Cognitive Impairment (MCI)

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