Trial intelligence / Profile preview

LuPARP: 177Lu-PSMA-617 and Olaparib in mCRPC

NCT03874884Phase 1Active, not recruiting

Sponsor
Peter MacCallum Cancer Centre
Start
Jul 2019
Primary completion
May 2025
Modality
Small Molecules, Peptide-Drug Conjugates
Countries
1
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Overview

Phase 1, open-label, single-arm trial of olaparib and lutetium lu 177 vipivotide tetraxetan in metastatic castration-resistant prostate cancer (mCRPC), sponsored by Peter MacCallum Cancer Centre. Primary endpoints: Dose Limiting Toxicities at 11 months, Maximum Tolerated Dose at 11 months and 1 more. Started Jul 2019; status: active, not recruiting.

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Drugs

olapariblutetium lu 177 vipivotide tetraxetan
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Conditions

metastatic castration-resistant prostate cancer (mCRPC)

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