Trial intelligence / Profile preview

Ponesimod and Propranolol Interaction Study

NCT03882255Phase 1Completed

Sponsor
Janssen Pharmaceutical
Start
Mar 2019
Primary completion
Aug 2019
Modality
Covalent Small Molecules, Molecular Glues, Classical Binding Small Molecules
Countries
1
01

Overview

Phase 1, randomised, double-blind trial of ponesimod in multiple sclerosis (MS) (3 arms), sponsored by Janssen Pharmaceutical. Primary endpoints: Maximum Decrease from Baseline in Mean Hourly Heart Rate (Emax HR) on Day 5, Maximum Decrease from Baseline in Mean Hourly Heart Rate (Emax HR) on Day 19 and 2 more. Started Mar 2019; status: completed.

02

Drugs

ponesimod
03

Conditions

multiple sclerosis (MS)

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