Trial intelligence / Profile preview

MEDI5395 plus Durvalumab in Advanced Solid Tumors

NCT03889275Phase 1Completed

Sponsor
MedImmune
Start
Oct 2019
Primary completion
Nov 2021
Modality
Gene Editing, Prophylactic Vaccines, Gene Silencing
Countries
2
01

Overview

Phase 1, open-label trial of MEDI5395 in solid tumor (advanced stage) (8 cohorts), sponsored by MedImmune. Primary endpoints: Number of Participants With Treatment Emergent Adverse Events (TEAEs) and Treatment Emergent Serious Adverse Events (TESAEs) at 14.4 months, Number of Participants with Dose-limiting Toxicities at 28 days and 8 more. Started Oct 2019; status: completed.

02

Drugs

MEDI5395
03

Conditions

solid tumor (advanced stage)

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