Trial intelligence / Profile preview

Fazirsiran in Alpha-1 Antitrypsin Deficiency

NCT03945292Phase 2Completed

Sponsor
Arrowhead Pharmaceuticals
Start
Aug 2019
Primary completion
Nov 2021
Modality
Antisense DNA, Conjugated siRNA, MicroRNA (miRNA)
Countries
6
01

Overview

Phase 2, randomised, double-blind trial of fazirsiran in alpha-1 antitrypsin deficiency (AATD) (4 arms), sponsored by Arrowhead Pharmaceuticals. Primary endpoint: Percent Change From Baseline in Serum Z-Alpha-1 Antitrypsin at 16 weeks. Started Aug 2019; status: completed.

02

Drugs

fazirsiran
03

Conditions

alpha-1 antitrypsin deficiency (AATD)

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