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Sildenafil and Pulmonary Hypertension in Divers
NCT03945643Phase 1Completed
- Sponsor
- University of Oregon
- Start
- Jul 2019
- Primary completion
- Jan 2023
- Modality
- Small Molecules
- Countries
- 1
01
Overview
Phase 1, randomised, double-blind trial in pulmonary arterial hypertension (PAH) comparing Sildenafil with Placebo (2 arms). Primary endpoints: Pulmonary Pressure, Concentration of Biomarkers (Myoglobin, MRP8/14, NGAL, CRP, MMP-2, OPN, SAA, IGFBP-4, ICAM-1, VCAM-1, MMP-9, Cystatin C) and 1 more. Started Jul 2019; status: completed.
02
Drugs
sildenafil
03
Conditions
pulmonary arterial hypertension (PAH)
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