Trial intelligence / Profile preview

Pembrolizumab, Decitabine +/- Venetoclax in Relapsed/Refractory AML or MDS

NCT03969446Phase 1Suspended

Sponsor
City of Hope
Start
May 2020
Primary completion
Jul 2027
Modality
Immune Checkpoint Inhibitors, Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 1, open-label trial of pembrolizumab in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) (3 cohorts), sponsored by City of Hope. Primary endpoints: Incidence of adverse events at 2 years, Maximum-tolerated dose at 42 days and 1 more. Started May 2020; status: suspended.

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Drugs

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Conditions

acute myeloid leukemia (AML)myelodysplastic syndrome (MDS)

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