Trial intelligence / Profile preview

Pembrolizumab Alone or With Entinostat in Muscle-Invasive Bladder Cancer

NCT03978624Phase 2Active, not recruiting

Sponsor
UNC Lineberger Comprehensive Cancer Center
Start
Sep 2020
Primary completion
Mar 2024
Modality
Small Molecules
Countries
1
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Overview

Phase 2, open-label trial of pembrolizumab and entinostat in muscle-invasive bladder cancer (MIBC) (2 arms), sponsored by UNC Lineberger Comprehensive Cancer Center. Primary endpoint: Changes in CD8 T Cell Immune Gene Signature at 10 weeks. Started Sep 2020; status: active, not recruiting.

02

Drugs

pembrolizumabentinostat
03

Conditions

muscle-invasive bladder cancer (MIBC)

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