Trial intelligence / Profile preview

Personalized DNA Vaccine in Pediatric Recurrent CNS Tumors

NCT03988283Phase 1Recruiting

Sponsor
Washington University School of Medicine
Start
Oct 2024
Primary completion
Mar 2029
Modality
Prophylactic Vaccines, DNA Vaccines
Countries
1
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Overview

Phase 1, open-label, single-arm trial of polyepitope neoantigen dna vaccine in central nervous system tumor, sponsored by Washington University School of Medicine. Primary endpoints: Safety and tolerability of adjuvant personalized neoantigen DNA vaccine at 13 months and Feasibility of adjuvant personalized neoantigen DNA vaccine. Started Oct 2024; status: recruiting.

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Drugs

polyepitope neoantigen dna vaccine
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Conditions

central nervous system tumor

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