Trial intelligence / Profile preview

BH4 for Muscle Dysfunction in COPD

NCT04014712Phase 1Withdrawn

Sponsor
University of Massachusetts Amherst
Start
Apr 2021
Primary completion
Aug 2022
Modality
Allosteric Modulators, Metabolically Activated Prodrugs
Countries
1
01

Overview

Phase 1, randomised, double-blind trial of sapropterin in chronic obstructive pulmonary disease (COPD), sponsored by University of Massachusetts Amherst. Primary endpoints: Mitochondrial function at 4 hours and intracellular PO2 at 4 hours. Planned start Apr 2021; status: withdrawn.

02

Drugs

sapropterin
03

Conditions

chronic obstructive pulmonary disease (COPD)

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