Trial intelligence / Profile preview

Oral Abuse Potential of Nalbuphine in Recreational Opioid Users

NCT04018664Phase 1Completed

Sponsor
Trevi Therapeutics
Start
May 2018
Primary completion
Dec 2018
Modality
Orthosteric Ligands
Countries
1
01

Overview

Phase 1, randomised, double-blind trial of nalbuphine in prurigo nodularis (PN) (8 arms), sponsored by Trevi Therapeutics. Primary endpoints: Identification of appropriate low, intermediate, and high doses of nalbuphine solution at 24 hours and Oral abuse potential relative to hydromorphone and placebo at 24 hours. Started May 2018; status: completed.

02

Drugs

nalbuphine
03

Conditions

prurigo nodularis (PN)

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