Trial intelligence / Profile preview

Encorafenib, Binimetinib, and Nivolumab in MSS BRAF V600E mCRC

NCT04044430Phase 1Terminated

Sponsor
University of California, San Francisco
Start
Aug 2020
Primary completion
Jul 2022
Modality
Small Molecules, Monoclonal Antibodies
Countries
1
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Overview

Phase 1, open-label, single-arm trial of encorafenib, binimetinib and nivolumab in metastatic colorectal cancer (mCRC), sponsored by University of California, San Francisco. Primary endpoints: Overall Response Rate up to 3 years and Incidence of treatment-related grade 3 or higher adverse events. Started Aug 2020; status: terminated.

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Drugs

encorafenibbinimetinibnivolumab
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Conditions

metastatic colorectal cancer (mCRC)

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