Trial intelligence / Profile preview

PrEPVacc: HIV Vaccine and PrEP Efficacy Trial

NCT04066881Phase 2Completed

Sponsor
MRC/UVRI and LSHTM Uganda Research Unit
Start
Dec 2020
Primary completion
Dec 2024
Modality
Prophylactic Vaccines, Viral Vectors, Recombinant Proteins and Enzymes
Countries
1
01

Overview

Phase 2, randomised, double-blind trial of DNA-HIV-PT123, AIDSVAX B/E, CN54gp140, MVA-CMDR and tenofovir alafenamide in human immunodeficiency virus infection (HIV) (6 arms), sponsored by MRC/UVRI and LSHTM Uganda Research Unit. Primary endpoints: Incident HIV infection (Vaccine Analysis), Incident HIV infection (PrEP Analysis) and 1 more. Started Dec 2020; status: completed.

02

Drugs

DNA-HIV-PT123AIDSVAX B/ECN54gp140MVA-CMDRtenofovir alafenamide
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Conditions

human immunodeficiency virus infection (HIV)

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