Trial intelligence / Profile preview

PET Imaging of Inflammation and Lipid Lowering Study

NCT04073797Completed

Sponsor
University of Cambridge
Start
Mar 2023
Primary completion
May 2026
Modality
Antisense DNA, Nucleic Acid-Directed Small Molecules, Conjugated siRNA
Countries
1
01

Overview

Randomised, double-blind trial of inclisiran and colchicine in hypercholesterolemia, cardiovascular disease (CVD) and atherosclerosis (3 arms), sponsored by University of Cambridge. Primary endpoints: Carotid 68Ga-DOTATATE Positron Emission Tomography at 12 weeks and Carotid Ultrasound Plaque Structure Analysis imaging at 12 weeks. Started Mar 2023; status: completed.

02

Drugs

inclisirancolchicine
03

Conditions

hypercholesterolemiacardiovascular disease (CVD)atherosclerosis

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