Trial intelligence / Profile preview

Lazertinib and Amivantamab in Advanced Non-Small Cell Lung Cancer (Chrysalis-2)

NCT04077463Phase 1Active, not recruiting

Sponsor
Janssen Pharmaceutical
Start
Sep 2019
Primary completion
Feb 2027
Modality
Fragment-Derived Small Molecules, Monoclonal Antibodies, Bispecific Antibodies
Countries
10
01

Overview

Phase 1, open-label trial of lazertinib and amivantamab in non-small cell lung cancer (NSCLC) (9 arms), sponsored by Janssen Pharmaceutical. Primary endpoints: Dose-Limiting Toxicity at 21 days, Overall Response Rate up to 2.5 years and 3 more. Started Sep 2019; status: active, not recruiting.

02

Drugs

lazertinibamivantamab
03

Conditions

non-small cell lung cancer (NSCLC)

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