Trial intelligence / Profile preview

Topical Diclofenac and DFMO for Chemoprevention in Skin Cancer

NCT04091022Phase 2Completed

Sponsor
University of Alabama at Birmingham
Start
Jan 2021
Primary completion
Dec 2025
Modality
Transdermal Patches, Hydrogel Systems, Small Molecules
Countries
1
01

Overview

Phase 2, randomised, double-blind trial in non-melanoma skin cancer (NMSC) and actinic keratosis (AK) comparing Diclofenac + DFMO with Placebo + Placebo (2 arms). Primary endpoint: Reduction of actinic keratoses at 52 weeks. Started Jan 2021; status: completed.

02

Drugs

diclofenaceflornithine
03

Conditions

non-melanoma skin cancer (NMSC)actinic keratosis (AK)

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