Trial intelligence / Profile preview

Zanubrutinib in B-cell lymphoma patients intolerant to ibrutinib/acalabrutinib

NCT04116437Phase 2Completed

Sponsor
BeiGene
Start
Oct 2019
Primary completion
Jan 2026
Modality
Fragment-Derived Small Molecules, Reversible Covalent Inhibitors, Bivalent/Multivalent Binders
Countries
1
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Overview

Phase 2, open-label, single-arm trial of zanubrutinib in chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), Waldenström macroglobulinemia (WM) and 2 more, sponsored by BeiGene. Primary endpoint: Recurrence and change in severity of treatment-emergent Adverse Events of interest at 24 months. Started Oct 2019; status: completed.

02

Drugs

zanubrutinib
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Conditions

chronic lymphocytic leukemia (CLL)small lymphocytic lymphoma (SLL)Waldenström macroglobulinemia (WM)mantle cell lymphoma (MCL)marginal zone lymphoma (MZL)

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